6-Nitro-8-methoxy-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid
Aristolochic Acid D
CAS: 17413-38-6
Molecular Formula: C17H11NO8
6-Nitro-8-methoxy-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid - Names and Identifiers
6-Nitro-8-methoxy-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C17H11NO8 |
| Molar Mass | 357.27 |
| Melting Point | 262-263 °C(lit.) |
| Boling Point | 689.5°C |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents. |
| Appearance | Powder |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. |
6-Nitro-8-methoxy-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid - Reference
| Reference Show more | 1. [IF=7.46] Si-Qi Wu et al."Gold nanoclusters-based paper sensor for the visualized detection of nephrotoxic aristolochic acids."Sensor Actuat B-Chem. 2021 Aug;340:129792 |
6-Nitro-8-methoxy-10-hydroxyphenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid - Introduction
Aristolochic Acid D, chemical formula C17H16O7, is an organic acid. The following is a description of the nature, use, formulation and safety information of Aristolochic Acid D:
Nature:
1. Appearance: Aristolochic Acid D is a white to light yellow crystal or crystalline powder.
2. Solubility: Soluble in hot water, ethanol, dimethyl sulfoxide and dimethyl amide polar solvents.
3. Stability: It is relatively stable at room temperature, but the influence of heat, light and oxygen will cause decomposition reaction.
Use:
1. pharmaceutical field: Aristolochic Acid D is an intermediate of anti-tumor drug maleic acid methyl ester, which is used in the synthesis of anti-cancer drugs in the pharmaceutical field.
2. Agriculture: Aristolochic Acid D can be used as a plant growth regulator to promote plant growth and increase yield.
Preparation Method:
The synthesis of Aristolochic Acid D usually takes natural product aristolochic acid as raw material. The specific synthesis method mainly involves esterification, o-amidation and acid hydrolysis of aristolochic acid.
Safety Information:
1. Aristolochic Acid D has certain toxicity, attention should be paid to avoid contact with skin, eyes and respiratory tract. Wear appropriate personal protective equipment, such as gloves, goggles and masks.
2. Avoid pouring Aristolochic Acid D into the drain or the environment to avoid pollution to the environment.
3. During storage and transportation, care should be taken to avoid contact with flammable substances, oxidants and strong acids.
4. If you accidentally touch or ingest Aristolochic Acid D, please seek medical attention in time, and pay attention to the safety data sheet of the substance for your doctor's reference.
Please note that Aristolochic Acid D is a toxic substance and should only be synthesized and handled in a suitable laboratory or industrial environment and in accordance with relevant safe practices.
Nature:
1. Appearance: Aristolochic Acid D is a white to light yellow crystal or crystalline powder.
2. Solubility: Soluble in hot water, ethanol, dimethyl sulfoxide and dimethyl amide polar solvents.
3. Stability: It is relatively stable at room temperature, but the influence of heat, light and oxygen will cause decomposition reaction.
Use:
1. pharmaceutical field: Aristolochic Acid D is an intermediate of anti-tumor drug maleic acid methyl ester, which is used in the synthesis of anti-cancer drugs in the pharmaceutical field.
2. Agriculture: Aristolochic Acid D can be used as a plant growth regulator to promote plant growth and increase yield.
Preparation Method:
The synthesis of Aristolochic Acid D usually takes natural product aristolochic acid as raw material. The specific synthesis method mainly involves esterification, o-amidation and acid hydrolysis of aristolochic acid.
Safety Information:
1. Aristolochic Acid D has certain toxicity, attention should be paid to avoid contact with skin, eyes and respiratory tract. Wear appropriate personal protective equipment, such as gloves, goggles and masks.
2. Avoid pouring Aristolochic Acid D into the drain or the environment to avoid pollution to the environment.
3. During storage and transportation, care should be taken to avoid contact with flammable substances, oxidants and strong acids.
4. If you accidentally touch or ingest Aristolochic Acid D, please seek medical attention in time, and pay attention to the safety data sheet of the substance for your doctor's reference.
Please note that Aristolochic Acid D is a toxic substance and should only be synthesized and handled in a suitable laboratory or industrial environment and in accordance with relevant safe practices.
Last Update：2024-04-09 15:16:25
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Product Name: Aristolochic Acid Impurity 3 (Aristolochic Acid D) Visit Supplier Webpage Request for quotationCAS: 17413-38-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Aristolochic Acid D Visit Supplier Webpage Request for quotationCAS: 17413-38-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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